Concussion, Adrenal Fatigue, and Pregnenolone

Anti-depressants, prednisone, and cortisone are handed out like candy now at the doctor’s office. What they don’t tell you is that once you are on them you can’t get off, at least not quickly or without side effects. Finding what caused the change in brain and re-balance the chemistry would be a better option.

According to Dr. Merocla “Users and Doctors preferred the quick fix. However, these steroidal compounds proved to have serious downsides, including compromising the immune system and inducing osteoporosis, among other serious complications.” Research on pregnenolone halted in the 1950’s when cortisone became available as an immediate cure-all. Because pregnenolone, unlike cortisone, couldn’t be patented, pharmaceutical companies had no financial incentive to pursue the research.

Trauma can alter the brain chemistry and hormonal balance in both men and women. When the brain is stuck in a neurological loop of fight or flight, our hormones can get out of whack. The regions of the brain that are involved in the stress response include the amygdala, hippocampus, and prefrontal cortex. Traumatic stress can be associated with lasting changes in these brain areas, increasing cortisol and norepinephrine. Anti-depressants have been used to balance the hippocampus, but are often accompanied by severe side effects.

I was prescribed pregnenolone in 2004 for my head injury which resulted in the loss of hearing and constant migraines. At that time I did not understand the value of taking pregnenolone. I thought it was hormone therapy and decided not to take it long term, which now looking back was a mistake. My brain would have repaired faster, my chronic inflammation would have resolved, and my lymphatics would not have been compromised. 15 years later, I am prescribed pregnenolone again for my most recent concussions, and this time I am not going to make the same mistake. I need my brain back and it’s never too late.

Head trauma can compress the cranium, which physically can put pressure or reduce the space for the pituitary gland, often called the master hormone as it involves so many processes such as:

  1. Thyroid
  2. Reproductive organs
  3. Adrenal glands

How can you tell if you might need to take pregnenolone? Do you have the following symptoms of adrenal fatigue? Similar to symptoms of concussion sufferers.

  1. Nervousness
  2. Difficulty building muscles
  3. Irritability
  4. Weakness
  5. Mental depression
  6. Inability to concentrate
  7. Moments of confusion
  8. Indigestion
  9. Feelings of frustration
  10. Poor memory
  11. Insomnia
  12. Dizziness
  13. Inflammation
  14. Poor resistance to infection

Pregnenolone has been reported to not only make people smarter and happier, but enhance one’s ability to perform on the job while heightening feelings of well-being. Pregnenolone has also been reported to reduce high stress induced fatigue.

Pregnenolone is a natural choice for brain repair and hormonal balancing after trauma or head injury. The precursor from which almost all of the other steroid hormones are made; including DHEA, progesterone, testosterone, the estrogens, and cortisol. Despite its powerful metabolites, pregnenolone is acknowledged to be without significant side effects and creates minimal or no anabolic, estrogenic, or androgenic activity.

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